Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 12/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733368 | 0.91 | CHRM2 (0.41) | CNR2MEN1KMT2AMKNK2MAPT | |
| SCHEMBL4730455 | 0.85 | USP30 (0.39) | TP53MKNK2MAPT | |
| SCHEMBL4731712 | 0.81 | ALDH1A1 (0.51) | CNR2MEN1KMT2A | |
| SCHEMBL4781177 | 0.80 | KMT2A (0.49) | KMT2ATP53MAPT | |
| SCHEMBL4732610 | 0.78 | NR2F2 (0.51) | MAPT | |
| SCHEMBL4730716 | 0.77 | SLC2A1 (0.45) | TP53 | |
| SCHEMBL4730919 | 0.76 | POLB (0.58) | MEN1KMT2A | |
| SCHEMBL4734747 | 0.75 | KMT2A (0.48) | MEN1KMT2ATP53MAPT | |
| SCHEMBL4733867 | 0.75 | MEN1 (0.46) | MEN1KMT2A | |
| SCHEMBL4731336 | 0.75 | CNR2 (0.39) | CNR2MEN1KMT2ACNR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061029-A1 | ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | claimed |
| WO-2008061029-A1 | ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |