Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 3/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4732673 | 0.92 | CNR2 (0.40) | CNR2PKMNPY1RNPY5RDRD2 | |
| SCHEMBL4733373 | 0.90 | BRD4 (0.40) | CNR2PKMTSHRTP53NAMPT | |
| SCHEMBL4733893 | 0.85 | KDM4E (0.38) | TSHRTP53HTTCCR8 | |
| SCHEMBL4733838 | 0.82 | PSMD14 (0.43) | CNR2PKM | |
| SCHEMBL4732817 | 0.80 | CNR2 (0.39) | CNR2PKMTSHRGBA1CNR1 | |
| SCHEMBL4729711 | 0.80 | ALDH1A1 (0.52) | PKMTSHR | |
| SCHEMBL4733963 | 0.79 | CNR2 (0.38) | CNR2PKMTSHRGBA1CNR1 | |
| SCHEMBL4731794 | 0.79 | CYP3A4 (0.49) | PKMTSHR | |
| SCHEMBL4730155 | 0.78 | CNR2 (0.39) | CNR2PKMTSHRGBA1CNR1 | |
| SCHEMBL4732243 | 0.78 | CNR2 (0.39) | CNR2PKMTSHRGBA1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061029-A1 | ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | claimed |
| WO-2008061029-A1 | ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |