Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 7/20 | 0.67 |
| ▸ | BCR | P11274 | 6/20 | 0.67 |
| ▸ | LCK | P06239 | 2/20 | 0.64 |
| ▸ | RET | P07949 | 2/20 | 0.53 |
| ▸ | PRKCA | P17252 | 3/20 | 0.48 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.46 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 5/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | ITK | Q08881 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30078200 | 0.84 | ABL1 (0.66) | ABL1BCRLCKRETPRKCA | |
| SCHEMBL24885526 | 0.84 | ABL1 (0.66) | ABL1BCRLCKRETPRKCA | |
| SCHEMBL4893292 | 0.84 | ABL1 (0.65) | ABL1BCRLCKRETPRKCA | |
| SCHEMBL7601457 | 0.82 | ABL1 (0.78) | ABL1BCRLCKRETPRKCA | |
| SCHEMBL4269629 | 0.81 | ABL1 (0.66) | ABL1BCRLCKRETPRKCA | |
| Hydrochloric Acid SCHEMBL5205211 | 0.81 | ABL1 (0.76) | ABL1BCRLCKRETPRKCA | |
| SCHEMBL2616948 | 0.81 | ABL1 (0.59) | ABL1BCRLCKRETPRKCA | |
| SCHEMBL2392 | 0.81 | ABL1 (1.00) | ABL1BCRPRKCASRCPDGFRB | |
| SCHEMBL29555505 | 0.81 | ABL1 (1.00) | ABL1BCRPRKCASRCPDGFRB | |
| SCHEMBL29366999 | 0.81 | ABL1 (1.00) | ABL1BCRPRKCASRCPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8466154-B2 | Methods and compositions related to wrapping of dehydrons | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2013-06-18 | — | — | US | disclosed |
| US-20130131076-A1 | METHODS AND COMPOSITIONS RELATED TO WRAPPING OF DEHYDRONS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2013-05-23 | — | — | US | disclosed |
| WO-2008070350-A9 | METHODS AND COMPOSITIONS RELATED TO WRAPPING OF DEHYDRONS | UNIV TEXAS (US) | 2008-10-23 | — | — | WO | disclosed |
| WO-2008070350-A2 | METHODS AND COMPOSITIONS RELATED TO WRAPPING OF DEHYDRONS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2008-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131076-A1 | METHODS AND COMPOSITIONS RELATED TO WRAPPING OF DEHYDRONS | DKK1, HPN, OSBP2 | ABL1 3511/4885BCR 510/4885LCK 1807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.