Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PTPRB | P23467 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28256465 | 0.79 | TSHR (0.55) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL16209873 | 0.79 | TSHR (0.55) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL27688950 | 0.78 | TSHR (0.48) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL27994582 | 0.78 | TSHR (0.60) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL759137 | 0.77 | TSHR (0.52) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL8629503 | 0.76 | LMNA (0.36) | TSHRLMNAKDM4EALDH1A1MAPT | |
| SCHEMBL19616629 | 0.76 | TSHR (0.57) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL2118005 | 0.76 | TSHR (0.50) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL9666722 | 0.76 | TSHR (0.50) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL27834061 | 0.76 | TSHR (0.50) | TSHRKMT2AMEN1LMNACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061363-A1 | BIOMOLECULE COMPATIBLE SILICA PARTICLES | MCMASTER UNIVERSITY (CA) | 2008-05-29 | — | — | WO | disclosed |