Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8633741 | 0.89 | FDPS (0.39) | LMNAADRB3FDPSPDE4DPDE3A | |
| SCHEMBL8633101 | 0.85 | FDPS (0.42) | LMNAFDPSPDE3ATSHRALDH1A1 | |
| SCHEMBL31047206 | 0.79 | DGAT1 (0.45) | LMNAADRB3FDPSPDE4DPDE3A | |
| SCHEMBL4733951 | 0.76 | TSHR (0.52) | LMNAKDM4ETSHRALDH1A1MAPT | |
| SCHEMBL1555747 | 0.75 | DGAT1 (0.39) | LMNAADRB3FDPSPDE4DPDE3A | |
| Hydrochloric Acid SCHEMBL4316792 | 0.73 | DGAT1 (0.38) | LMNAADRB3FDPSPDE4DPDE3A | |
| SCHEMBL18943050 | 0.73 | DGAT1 (0.33) | LMNAADRB3FDPSPDE4DPDE3A | |
| SCHEMBL27593964 | 0.73 | ODC1 (0.38) | LMNAADRB3FDPSPDE4DPDE3A | |
| Ethylenediamine SCHEMBL27703572 | 0.72 | DGAT1 (0.41) | LMNADGAT1KDM4ETSHRKCNN4 | |
| SCHEMBL3822810 | 0.72 | LMNA (0.36) | LMNAADRB3FDPSPDE4DPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773465-A | Tartronic acids, their acetalic ethers and o-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1998-06-30 | — | — | US | disclosed |
| US-5656656-A | Tartronic acids, their acetalic ethers and O-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1997-08-12 | — | — | US | disclosed |
| EP-0667850-B1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE FARMACEUTICI SPA (IT) | 1997-05-28 | — | — | EP | disclosed |
| EP-0667850-A1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS. | DOMPE FARMACEUTICI SPA (IT) | 1995-08-23 | — | — | EP | disclosed |
| CN-1091741-A | Tartronic acid and acetal ether thereof and O-ester | DOMPE FARMACEUTICI SPA (IT) | 1994-09-07 | — | — | CN | disclosed |
| WO-1994010127-A1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE' FARMACEUTICI S.P.A. (IT) | 1994-05-11 | — | — | WO | disclosed |