Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | MAPK10 | P53779 | 2/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | RGS12 | O14924 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4734498 | 0.88 | LMNA (0.78) | LMNAMAPK10POLBALDH1A1HPGD | |
| SCHEMBL4752208 | 0.82 | LMNA (0.69) | LMNAMAPK10POLBALDH1A1HPGD | |
| SCHEMBL4752211 | 0.81 | LMNA (0.68) | LMNAMAPK10POLBALDH1A1HPGD | |
| SCHEMBL4732827 | 0.80 | L3MBTL1 (1.00) | LMNAMAPK10ALDH1A1L3MBTL1TSHR | |
| SCHEMBL14478894 | 0.79 | LMNA (0.65) | LMNAMAPK10ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL3456222 | 0.77 | HPGD (0.68) | LMNAMAPK10POLBALDH1A1HPGD | |
| SCHEMBL10502377 | 0.76 | KMT2A (1.00) | MAPK10POLBALDH1A1L3MBTL1MAPT | |
| SCHEMBL4732905 | 0.76 | L3MBTL1 (0.81) | LMNAMAPK10POLBALDH1A1L3MBTL1 | |
| SCHEMBL3431552 | 0.76 | KMT2A (0.91) | POLBALDH1A1HPGDMAPTRGS12 | |
| SCHEMBL4733849 | 0.75 | LMNA (0.60) | LMNAMAPK10POLBALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008069611-A1 | N-PHENYLAMIDE DERIVATIVE, PROCESS FOR THE PREPARATION THEREOF, AND COMPOSITION FOR PREVENTING OR TREATING ISCHEMIC DISEASES COMPRISING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-06-12 | — | — | WO | claimed |
| US-9364468-B2 | Pharmaceutical composition for preventing or treating tuberculosis | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2016-06-14 | — | — | US | disclosed |
| US-9364468-B2 | Pharmaceutical composition for preventing or treating tuberculosis | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2016-06-14 | — | — | US | disclosed |
| US-20150133503-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING TUBERCULOSIS | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2015-05-14 | — | — | US | disclosed |
| US-20150133503-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING TUBERCULOSIS | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2015-05-14 | — | — | US | disclosed |
| WO-2008069611-A1 | N-PHENYLAMIDE DERIVATIVE, PROCESS FOR THE PREPARATION THEREOF, AND COMPOSITION FOR PREVENTING OR TREATING ISCHEMIC DISEASES COMPRISING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150133503-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING TUBERCULOSIS | GCDH, DHODH, MDH1 | LMNA 3805/4885MAPK10 4027/4885POLB 1770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.