Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6532346 | 0.86 | ITGB1 (0.41) | LMNAMAPTCRHBPCRHR2L3MBTL1 | |
| SCHEMBL4734251 | 0.85 | PPID (0.46) | LMNAITGB1ITGA4ELANE | |
| SCHEMBL6131675 | 0.84 | MAPT (0.37) | LMNAMAPTCRHBPCRHR2L3MBTL1 | |
| SCHEMBL4736909 | 0.81 | MAPT (0.56) | LMNAMAPTCRHBPCRHR2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL7986763 | 0.78 | LMNA (0.47) | LMNAMAPTCRHBPCRHR2L3MBTL1 | |
| SCHEMBL4737029 | 0.78 | BCHE (0.41) | LMNAMAPTALDH1A1ITGA4ELANE | |
| SCHEMBL4737032 | 0.78 | BCHE (0.41) | LMNAMAPTALDH1A1ITGA4ELANE | |
| SCHEMBL28209573 | 0.76 | LMNA (0.46) | LMNAMAPTCRHBPCRHR2L3MBTL1 | |
| SCHEMBL7357530 | 0.74 | MEN1 (0.46) | LMNAMAPTCRHBPCRHR2L3MBTL1 | |
| SCHEMBL7357526 | 0.74 | MEN1 (0.46) | LMNAMAPTCRHBPCRHR2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008064830-A1 | BICYCLIC AND HETEROBICYCLIC DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR PHARMACEUTICAL USES | UCB PHARMA, S.A. (BE) | 2008-06-05 | — | — | WO | claimed |
| WO-2008064830-A1 | BICYCLIC AND HETEROBICYCLIC DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR PHARMACEUTICAL USES | UCB PHARMA, S.A. (BE) | 2008-06-05 | — | — | WO | disclosed |