Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 2/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | HTR1E | P28566 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | USP21 | Q9UK80 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6131675 | 0.90 | MAPT (0.37) | LMNAKCNJ1KCNH2ALDH1A1SMN1; SMN2 | |
| SCHEMBL6131661 | 0.87 | ITGB1 (0.50) | ITGB1ITGA4LMNAALDH1A1MAPT | |
| SCHEMBL6131662 | 0.87 | ITGB1 (0.50) | ITGB1ITGA4LMNAALDH1A1MAPT | |
| SCHEMBL4750224 | 0.86 | ITGB1 (0.44) | ITGB1ITGA4LMNAL3MBTL1CYP1A2 | |
| SCHEMBL4750220 | 0.86 | ITGB1 (0.44) | ITGB1ITGA4LMNAL3MBTL1CYP1A2 | |
| SCHEMBL4734050 | 0.86 | LMNA (0.41) | ITGB1ITGA4LMNAKCNJ1KCNH2 | |
| SCHEMBL4736967 | 0.84 | TDP1 (0.44) | ITGB1ITGA4LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL4737032 | 0.84 | BCHE (0.41) | ITGA4LMNAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4737029 | 0.84 | BCHE (0.41) | ITGA4LMNAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6131678 | 0.83 | ITGB1 (0.46) | ITGB1ITGA4CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1525181-A1 | PROCESS FOR THE PREPARATION OF PHENYLALANINE ENAMIDE DERIVATIVES | Celltech R & D Limited (GB) | 2005-04-27 | — | — | EP | disclosed |
| WO-2004007428-A1 | PROCESS FOR THE PREPARATION OF PHENYLALANINE ENAMIDE DERIVATIVES | CELLTECH R & D LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |