Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 8/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737029 | 1.00 | BCHE (0.41) | BCHEITGA4ITGB7MMP1CTSL | |
| SCHEMBL4734039 | 0.88 | MMP1 (0.42) | MMP1ELANE | |
| SCHEMBL4734043 | 0.88 | MMP1 (0.42) | MMP1ELANE | |
| SCHEMBL6532346 | 0.84 | ITGB1 (0.41) | ITGA4ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL6131675 | 0.82 | MAPT (0.37) | ELANEALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL4736897 | 0.80 | MMP1 (0.39) | ITGA4MMP1ELANE | |
| SCHEMBL4734050 | 0.78 | LMNA (0.41) | ITGA4ELANEALDH1A1LMNAMAPT | |
| SCHEMBL6131689 | 0.74 | L3MBTL1 (0.36) | ITGA4ITGB7CTSLMAPTSMN1; SMN2 | |
| SCHEMBL6131662 | 0.73 | ITGB1 (0.50) | ITGA4ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL6131661 | 0.73 | ITGB1 (0.50) | ITGA4ALDH1A1LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008064830-A1 | BICYCLIC AND HETEROBICYCLIC DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR PHARMACEUTICAL USES | UCB PHARMA, S.A. (BE) | 2008-06-05 | — | — | WO | claimed |
| WO-2008064830-A1 | BICYCLIC AND HETEROBICYCLIC DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR PHARMACEUTICAL USES | UCB PHARMA, S.A. (BE) | 2008-06-05 | — | — | WO | disclosed |