Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.42 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6575563 | 0.90 | ALDH1A1 (0.46) | LMNAMAPTKMT2AALDH1A1GAA | |
| SCHEMBL27400595 | 0.85 | KMT2A (0.47) | LMNAMAPTKMT2APKMKDM4E | |
| Hydrochloric Acid SCHEMBL7986763 | 0.84 | LMNA (0.47) | LMNAMAPTCRHBPCRHR2KMT2A | |
| SCHEMBL6575607 | 0.84 | CTSL (0.43) | LMNAMAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL28052118 | 0.82 | CA2 (0.54) | LMNAMAPTKMT2AMEN1ITGA4 | |
| SCHEMBL6891119 | 0.81 | CA2 (0.47) | LMNAMAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL4538023 | 0.81 | HDAC1 (0.45) | LMNAMAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL4538019 | 0.81 | HDAC1 (0.45) | LMNAMAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL7882117 | 0.81 | MMP8 (0.55) | KMT2AALDH1A1GAAMEN1 | |
| SCHEMBL6952367 | 0.81 | MMP8 (0.55) | KMT2AALDH1A1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107935875-A | A kind of synthetic method of melphalan | 兆科药业（广州）有限公司 | 2018-04-20 | — | — | CN | disclosed |