Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | PRKAA2 | P54646 | 5/20 | 0.52 |
| ▸ | PRKAB2 | O43741 | 3/20 | 0.52 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.52 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.52 |
| ▸ | PRKAG3 | Q9UGI9 | 3/20 | 0.52 |
| ▸ | PRKAG2 | Q9UGJ0 | 3/20 | 0.52 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13202942 | 0.85 | RAB9A (0.57) | EPHX2RAB9APRKAA2PRKAB2PRKAG1 | |
| SCHEMBL4616966 | 0.83 | EPHX2 (0.59) | EPHX2RAB9APRKAA2PRKAB2PRKAG1 | |
| SCHEMBL4534421 | 0.82 | MAPT (0.67) | EPHX2RAB9AHPGDSMN1; SMN2GRM5 | |
| SCHEMBL4617713 | 0.82 | GFER (0.53) | EPHX2EPHX1MEN1KMT2A | |
| SCHEMBL23573470 | 0.81 | SFRP1 (0.57) | EPHX2PRKAA2PRKAB2PRKAG1PRKAA1 | |
| SCHEMBL6102058 | 0.81 | HPGDS (0.57) | EPHX2PRKAA2PRKAB2PRKAG1PRKAA1 | |
| SCHEMBL4736618 | 0.81 | RAB9A (0.58) | EPHX2RAB9AHPGDSFRP1SMN1; SMN2 | |
| SCHEMBL8434306 | 0.80 | RAB9A (0.64) | EPHX2RAB9AHPGDSMN1; SMN2GRM5 | |
| SCHEMBL16973635 | 0.80 | PRKAA2 (0.44) | EPHX2PRKAA2PRKAB2PRKAG1PRKAA1 | |
| SCHEMBL2001638 | 0.78 | AKR1C3 (0.50) | EPHX2PRKAA2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210198239-A1 | COMPOUNDS AND METHODS FOR CD73 MODULATION AND INDICATIONS THEREFOR | PLEXXIKON INC. | 2021-07-01 | — | — | US | disclosed |
| WO-2008061016-A1 | N-SUBSTITUTED PIPERIDINYL 4 -ARYLSULFONAMIDES AS MODULATORS OF THE SECRETED FRIZZLED RELATED PROTEIN- 1 | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210198239-A1 | COMPOUNDS AND METHODS FOR CD73 MODULATION AND INDICATIONS THEREFOR | ENTPD5, ADORA2A, ENTPD1 | EPHX2 959/4885RAB9A 2930/4885PRKAA2 2641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.