Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10721682 | 0.80 | CA1 (0.52) | CA12CA1CA2CA4CA5A | |
| SCHEMBL10722266 | 0.73 | LTA4H (0.54) | CA12CA1CA2CA4CA5A | |
| SCHEMBL384926 | 0.73 | HPGD (0.54) | CA12CA1CA2CA4CA5A | |
| SCHEMBL14204718 | 0.72 | HKDC1 (0.40) | CA12CA1CA2CA4CA5A | |
| SCHEMBL25432574 | 0.71 | HKDC1 (0.38) | CA12CA1CA2CA4CA5A | |
| SCHEMBL17923949 | 0.71 | UTRN (0.39) | CA12CA1CA2CA4CA5A | |
| SCHEMBL2030797 | 0.71 | TDP1 (0.42) | CA12CA1CA2CA4CA5A | |
| SCHEMBL11804299 | 0.71 | ALOX15 (0.43) | CA12CA1CA2CA4CA5A | |
| SCHEMBL914784 | 0.71 | HKDC1 (0.53) | CA12CA1CA2CA4CA5A | |
| SCHEMBL499887 | 0.70 | L3MBTL1 (0.56) | CA12CA1CA2CA4CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061238-A2 | PROCESSES FOR PRODUCTION OF 4-BIPHENYLYAZETIDIN-2-ONES | IRONWOOD PHARMACEUTICALS, INC. (US) | 2008-05-22 | — | — | WO | disclosed |