SCHEMBL4734307 — predicted protein targets

Predicted protein targets (top 16)

	gene	UniProt	supporting neighbours	confidence
▸	SFRP1	Q8N474	7/20	0.47

▸	L3MBTL1	Q9Y468	2/20	0.41

▸	CCNT1	O60563	1/20	0.41

▸	RAB9A	P51151	1/20	0.39

▸	EPHX1	P07099	1/20	0.38

▸	EPHX2	P34913	1/20	0.38

▸	CCR8	P51685	1/20	0.38

▸	LMNA	P02545	1/20	0.38

▸	PKM	P14618	1/20	0.37

▸	ALDH1A1	P00352	1/20	0.37

▸	HTT	P42858	1/20	0.37

▸	PKLR	P30613	1/20	0.36

▸	ACLY	P53396	1/20	0.36

▸	CYP3A4	P08684	1/20	0.36

▸	CYP2C9	P11712	1/20	0.36

▸	CYP2C19	P33261	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL4734889	0.86	SFRP1 (0.47)	SFRP1L3MBTL1CCNT1RAB9AEPHX1
SCHEMBL4734739	0.78	SFRP1 (0.43)	SFRP1EPHX1EPHX2CCR8LMNA
SCHEMBL4736713	0.69	SFRP1 (0.69)	SFRP1EPHX1EPHX2CCR8CYP2C9
SCHEMBL4730886	0.68	MEN1 (0.36)	SFRP1RAB9ACCR8LMNAALDH1A1
SCHEMBL4730880	0.68	MEN1 (0.36)	SFRP1RAB9ACCR8LMNAALDH1A1
SCHEMBL4737077	0.67	SFRP1 (0.68)	SFRP1EPHX2
SCHEMBL4618350	0.64	SFRP1 (0.77)	SFRP1
SCHEMBL4782444	0.64	SFRP1 (1.00)	SFRP1
SCHEMBL13866415	0.64	GAA (0.60)	EPHX1EPHX2PKMALDH1A1HTT
SCHEMBL16000511	0.63	GAA (0.59)	EPHX1EPHX2PKMALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2008061029-A1	ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE	WYETH (US)	2008-05-22	—	—	WO	disclosed