Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | PPID | Q08752 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2687930 | 0.89 | ALDH1A1 (0.46) | L3MBTL1ALDH1A1KMT2AMAPK1TDP1 | |
| SCHEMBL4734508 | 0.86 | ALDH1A1 (0.41) | L3MBTL1ALDH1A1RAB9AKMT2ANPC1 | |
| SCHEMBL2687931 | 0.83 | CASP1 (0.37) | L3MBTL1ALDH1A1KMT2AELANEMAPK1 | |
| SCHEMBL2690002 | 0.74 | PPID (0.36) | ADORA3PPIDL3MBTL1ALDH1A1RAB9A | |
| SCHEMBL28836748 | 0.73 | ALDH1A1 (0.49) | PPIDL3MBTL1ALDH1A1RAB9AKMT2A | |
| SCHEMBL4403270 | 0.73 | ALDH1A1 (0.52) | L3MBTL1ALDH1A1KMT2AMAPK1TDP1 | |
| SCHEMBL17088183 | 0.72 | TSHR (0.36) | L3MBTL1ALDH1A1KMT2ATSHRMAPT | |
| SCHEMBL28113526 | 0.72 | ALDH1A1 (0.50) | PPIDL3MBTL1ALDH1A1RAB9AKMT2A | |
| SCHEMBL28675001 | 0.72 | ALDH1A1 (0.47) | ADORA3PPIDL3MBTL1ALDH1A1RAB9A | |
| SCHEMBL15114506 | 0.72 | ALDH1A1 (0.44) | L3MBTL1ALDH1A1KMT2AMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061363-A1 | BIOMOLECULE COMPATIBLE SILICA PARTICLES | MCMASTER UNIVERSITY (CA) | 2008-05-29 | — | — | WO | disclosed |