Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4734508 | 0.91 | ALDH1A1 (0.41) | ALDH1A1MAPK1L3MBTL1HCAR2KMT2A | |
| SCHEMBL4734515 | 0.89 | ADORA3 (0.39) | ALDH1A1MAPK1L3MBTL1KMT2ASLC6A2 | |
| SCHEMBL2687931 | 0.83 | CASP1 (0.37) | ALDH1A1MAPK1L3MBTL1SLC15A1KMT2A | |
| SCHEMBL3282967 | 0.80 | ALDH1A1 (0.54) | ALDH1A1MAPK1L3MBTL1HCAR2SLC15A1 | |
| SCHEMBL4403270 | 0.77 | ALDH1A1 (0.52) | ALDH1A1MAPK1L3MBTL1SLC15A1KMT2A | |
| SCHEMBL242004 | 0.76 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1HCAR2SLC15A1 | |
| SCHEMBL20221612 | 0.76 | ALDH1A1 (0.44) | ALDH1A1MAPK1L3MBTL1HCAR2KMT2A | |
| SCHEMBL15114506 | 0.76 | ALDH1A1 (0.44) | ALDH1A1MAPK1L3MBTL1HCAR2KMT2A | |
| SCHEMBL11064051 | 0.75 | PKM (0.57) | ALDH1A1MAPK1L3MBTL1HCAR2KMT2A | |
| SCHEMBL17895893 | 0.75 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1HCAR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168741-B2 | Chelating silicon-based polymers | JOINT INTELLECTUAL PROPERTY POLICY OF MCMASTER UNIVERSITY (CA) | 2012-05-01 | — | — | US | disclosed |
| US-8168741-B2 | Chelating silicon-based polymers | JOINT INTELLECTUAL PROPERTY POLICY OF MCMASTER UNIVERSITY (CA) | 2012-05-01 | — | — | US | disclosed |
| US-20090118456-A1 | CHELATING SILICON-BASED POLYMERS | MCMASTER UNIVERSITY (CA) | 2009-05-07 | — | — | US | disclosed |
| US-20090118456-A1 | CHELATING SILICON-BASED POLYMERS | MCMASTER UNIVERSITY (CA) | 2009-05-07 | — | — | US | disclosed |
| EP-1915385-A1 | CHELATING SILICON-BASED POLYMERS | McMaster University (CA) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007014471-A1 | CHELATING SILICON-BASED POLYMERS | MCMASTER UNIVERSITY (CA) | 2007-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118456-A1 | CHELATING SILICON-BASED POLYMERS | SRM, SMURF1, SLC39A14 | ALDH1A1 4478/4885MAPK1 4503/4885L3MBTL1 3625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.