Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 6/20 | 0.41 |
| ▸ | CTSA | P10619 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783818 | 0.87 | MAPT (0.38) | HIF1AEGLN1 | |
| SCHEMBL20509577 | 0.76 | ALDH1A1 (0.47) | MEN1KMT2A | |
| SCHEMBL4734620 | 0.72 | MKNK1 (0.43) | CTSAGRIN2B | |
| SCHEMBL6264166 | 0.71 | MAPT (0.53) | HIF1ACTSAUSP30MEN1KMT2A | |
| SCHEMBL4782035 | 0.71 | RECQL (0.57) | HIF1AMEN1KMT2A | |
| SCHEMBL29929320 | 0.70 | HIF1A (0.55) | HIF1ACTSA | |
| SCHEMBL9683260 | 0.70 | ALDH1A1 (0.43) | HIF1AMEN1KMT2ATDP1 | |
| SCHEMBL28919959 | 0.70 | ALDH1A1 (0.43) | HIF1AMEN1KMT2ATDP1 | |
| SCHEMBL9683262 | 0.70 | ALDH1A1 (0.43) | HIF1AMEN1KMT2ATDP1 | |
| SCHEMBL71034 | 0.70 | HIF1A (0.55) | HIF1ACTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008070350-A9 | METHODS AND COMPOSITIONS RELATED TO WRAPPING OF DEHYDRONS | UNIV TEXAS (US) | 2008-10-23 | — | — | WO | disclosed |
| WO-2008070350-A2 | METHODS AND COMPOSITIONS RELATED TO WRAPPING OF DEHYDRONS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2008-06-12 | — | — | WO | disclosed |