Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | WNT3A | P56704 | 1/20 | 0.32 |
| ▸ | NEK2 | P51955 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4734617 | 0.87 | HIF1A (0.41) | HIF1AEGLN1 | |
| SCHEMBL20509577 | 0.75 | ALDH1A1 (0.47) | MAPTSMN1; SMN2HSD17B10KDM4ELMNA | |
| SCHEMBL5796703 | 0.75 | KDM4E (0.48) | MAPTSMN1; SMN2HSD17B10TSHRKDM4E | |
| SCHEMBL22492769 | 0.74 | HTT (0.46) | SMN1; SMN2HIF1AHSD17B10KDM4EHTT | |
| SCHEMBL5242504 | 0.74 | HTT (0.46) | SMN1; SMN2HIF1AHSD17B10KDM4EHTT | |
| SCHEMBL4783822 | 0.74 | MKNK1 (0.38) | MAPTSMN1; SMN2HSD17B10TSHRERN1 | |
| SCHEMBL4736050 | 0.71 | HTT (0.56) | MAPTSMN1; SMN2HIF1AROCK2HTT | |
| SCHEMBL31512829 | 0.70 | P4HTM (0.52) | MAPTHIF1AEGLN1KDM4ELMNA | |
| SCHEMBL26603874 | 0.69 | ALDH1A1 (0.48) | MAPTSMN1; SMN2EGLN1KDM4ELMNA | |
| SCHEMBL30617944 | 0.68 | GSK3B (0.54) | HIF1ATSHRCHEK2HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008070350-A9 | METHODS AND COMPOSITIONS RELATED TO WRAPPING OF DEHYDRONS | UNIV TEXAS (US) | 2008-10-23 | — | — | WO | disclosed |
| WO-2008070350-A2 | METHODS AND COMPOSITIONS RELATED TO WRAPPING OF DEHYDRONS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2008-06-12 | — | — | WO | disclosed |