Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 2/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.33 |
| ▸ | TUBB | P07437 | 3/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.33 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.33 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.33 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3784501 | 0.88 | KDM4E (0.50) | KDM4ETDP1ALDH1A1TYRTRIM24 | |
| SCHEMBL31452766 | 0.83 | ALDH1A1 (0.46) | KDM4ETDP1TRPA1ALDH1A1TP53 | |
| SCHEMBL5126473 | 0.78 | ALDH1A1 (0.45) | TDP1TRPA1ALDH1A1TP53TYR | |
| SCHEMBL23209631 | 0.78 | TYR (0.48) | KDM4ETRPA1ALDH1A1TYRTRIM24 | |
| SCHEMBL2135992 | 0.78 | TRPA1 (0.48) | KDM4ETDP1TRPA1ALDH1A1TP53 | |
| SCHEMBL31511495 | 0.77 | ALDH1A1 (0.43) | KDM4ETDP1TRPA1ALDH1A1TP53 | |
| SCHEMBL3783722 | 0.75 | KDM4E (0.50) | KDM4ETDP1ALDH1A1TYRTRIM24 | |
| SCHEMBL20607770 | 0.75 | TYR (0.46) | KDM4ETYRTRIM24TRIM33ERN1 | |
| SCHEMBL29951345 | 0.75 | SRC (0.46) | KDM4EALDH1A1TYRTRIM24TRIM33 | |
| SCHEMBL14797280 | 0.75 | SRC (0.46) | KDM4EALDH1A1TYRTRIM24TRIM33 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008077646-A1 | NON-STEROIDAL PROGESTERONE RECEPTOR MODULATORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-07-03 | — | — | WO | disclosed |