Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 5/20 | 0.65 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.65 |
| ▸ | NQO2 | P16083 | 4/20 | 0.65 |
| ▸ | TTR | P02766 | 3/20 | 0.65 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.65 |
| ▸ | ESR1 | P03372 | 2/20 | 0.65 |
| ▸ | ABL1 | P00519 | 2/20 | 0.65 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.65 |
| ▸ | BCR | P11274 | 2/20 | 0.65 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.65 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.65 |
| ▸ | TUBB | P07437 | 2/20 | 0.65 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.65 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.65 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.65 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.65 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.65 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.65 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4734779 | 1.00 | CYP1A1 (0.65) | CYP1A1CYP1B1NQO2TTRALOX5 | |
| SCHEMBL4731650 | 1.00 | CYP1A1 (0.65) | CYP1A1CYP1B1NQO2TTRALOX5 | |
| SCHEMBL5692873 | 0.87 | XDH (0.78) | CYP1B1KDM4EMEN1MAPTRAB9A | |
| SCHEMBL5692868 | 0.87 | XDH (0.78) | CYP1B1KDM4EMEN1MAPTRAB9A | |
| SCHEMBL4933805 | 0.86 | CYP1A1 (0.65) | CYP1A1CYP1B1NQO2TTRALOX5 | |
| SCHEMBL4933810 | 0.86 | CYP1A1 (0.65) | CYP1A1CYP1B1NQO2TTRALOX5 | |
| SCHEMBL2400847 | 0.85 | RELA (0.68) | CYP1A1CYP1B1NQO2CYP19A1CYP1A2 | |
| SCHEMBL2400852 | 0.85 | RELA (0.68) | CYP1A1CYP1B1NQO2CYP19A1CYP1A2 | |
| SCHEMBL4733208 | 0.85 | NPC1 (0.63) | CYP1A1CYP1B1NQO2TTRALOX5 | |
| SCHEMBL4733209 | 0.85 | NPC1 (0.63) | CYP1A1CYP1B1NQO2TTRALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426369-B2 | Prevention and treatment of colon cancer | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2013-04-23 | — | — | US | claimed |
| US-20120178704-A1 | PREVENTION AND TREATMENT OF COLON CANCER | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2012-07-12 | — | — | US | claimed |
| US-8426369-B2 | Prevention and treatment of colon cancer | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2013-04-23 | — | — | US | disclosed |
| US-20120178704-A1 | PREVENTION AND TREATMENT OF COLON CANCER | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2012-07-12 | — | — | US | disclosed |
| WO-2008070872-A1 | PREVENTION AND TREATMENT OF COLON CANCER | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2008-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178704-A1 | PREVENTION AND TREATMENT OF COLON CANCER | APC, SI, NFKBIA | CYP1A1 1123/4885CYP1B1 1133/4885NQO2 1440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.