Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.56 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.56 |
| ▸ | BCHE | P06276 | 9/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3069103 | 0.83 | L3MBTL1 (0.52) | HTR2CMCHR1L3MBTL1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4736117 | 0.82 | L3MBTL1 (0.51) | HTR2CMCHR1L3MBTL1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4782319 | 0.82 | L3MBTL1 (0.51) | HTR2CMCHR1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL4735454 | 0.80 | L3MBTL1 (0.55) | MCHR1L3MBTL1LMNASMN1; SMN2EPHX2 | |
| SCHEMBL4735257 | 0.79 | AURKA (0.52) | HTR2CMCHR1BCHEL3MBTL1LMNA | |
| SCHEMBL4740304 | 0.78 | LMNA (0.51) | HTR2CMCHR1BCHEL3MBTL1LMNA | |
| SCHEMBL3071309 | 0.77 | SMN1; SMN2 (0.46) | HTR2CMCHR1L3MBTL1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3058950 | 0.77 | SMN1; SMN2 (0.46) | HTR2CMCHR1L3MBTL1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3066991 | 0.77 | SMN1; SMN2 (0.46) | HTR2CMCHR1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL12444447 | 0.75 | L3MBTL1 (0.57) | L3MBTL1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |