Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3069103 | 0.85 | L3MBTL1 (0.52) | LMNAL3MBTL1HTR2CMCHR1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4736117 | 0.84 | L3MBTL1 (0.51) | LMNAL3MBTL1HTR2CMCHR1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4782319 | 0.84 | L3MBTL1 (0.51) | LMNAL3MBTL1HTR2CMCHR1SMN1; SMN2 | |
| SCHEMBL3816827 | 0.80 | LMNA (0.63) | LMNAL3MBTL1SMN1; SMN2CYP3A4MAPK14 | |
| Hydrochloric Acid SCHEMBL4736121 | 0.78 | LMNA (0.62) | LMNAL3MBTL1SMN1; SMN2CYP3A4MAPK14 | |
| SCHEMBL4735255 | 0.78 | HTR2C (0.56) | LMNAL3MBTL1HTR2CMCHR1SMN1; SMN2 | |
| SCHEMBL4735454 | 0.76 | L3MBTL1 (0.55) | LMNAL3MBTL1MCHR1SMN1; SMN2CYP3A4 | |
| SCHEMBL4740307 | 0.76 | AURKA (0.50) | LMNAHTR2CSMN1; SMN2MAPK14CTNNB1 | |
| SCHEMBL6077802 | 0.75 | L3MBTL1 (0.77) | LMNAL3MBTL1SMN1; SMN2CYP3A4MAPK14 | |
| SCHEMBL3071309 | 0.74 | SMN1; SMN2 (0.46) | LMNAL3MBTL1HTR2CMCHR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |