Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.48 |
| ▸ | KLK1 | P06870 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4736117 | 0.99 | L3MBTL1 (0.51) | L3MBTL1LMNACACNA1HSMN1; SMN2KLKB1 | |
| Hydrochloric Acid SCHEMBL4782319 | 0.99 | L3MBTL1 (0.51) | L3MBTL1LMNACACNA1HSMN1; SMN2KLKB1 | |
| SCHEMBL4735454 | 0.87 | L3MBTL1 (0.55) | L3MBTL1LMNASMN1; SMN2KLKB1KLK1 | |
| SCHEMBL4739795 | 0.87 | HDAC3 (0.51) | LMNAKLKB1KLK1AOC3MAPK1 | |
| SCHEMBL4740304 | 0.85 | LMNA (0.51) | L3MBTL1LMNASMN1; SMN2HTR2CMCHR1 | |
| SCHEMBL3071309 | 0.84 | SMN1; SMN2 (0.46) | L3MBTL1LMNASMN1; SMN2HTR2CMCHR1 | |
| Hydrochloric Acid SCHEMBL3058950 | 0.83 | SMN1; SMN2 (0.46) | L3MBTL1LMNASMN1; SMN2HTR2CMCHR1 | |
| Hydrochloric Acid SCHEMBL3066991 | 0.83 | SMN1; SMN2 (0.46) | L3MBTL1LMNASMN1; SMN2HTR2CMCHR1 | |
| SCHEMBL4735255 | 0.83 | HTR2C (0.56) | L3MBTL1LMNASMN1; SMN2HTR2CMCHR1 | |
| SCHEMBL3816827 | 0.80 | LMNA (0.63) | L3MBTL1LMNASMN1; SMN2EPHX2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267697-A1 | ION CHANNEL MODULATORS | WYETH (US) | 2010-10-21 | — | — | US | claimed |
| EP-2099754-A1 | ION CHANNEL MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2009-09-16 | — | — | EP | claimed |
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |
| WO-2008073929-A1 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |
| US-20100267697-A1 | ION CHANNEL MODULATORS | WYETH (US) | 2010-10-21 | — | — | US | disclosed |
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267697-A1 | ION CHANNEL MODULATORS | CACNA1E, CACNA1A, CACNA1S | L3MBTL1 3453/4885LMNA 2283/4885CACNA1H 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.