Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10585500 | 0.79 | CA1 (0.53) | GABRA1GABRB2LMNAKMT2AGABRB1 | |
| SCHEMBL7265720 | 0.78 | GABRA1 (0.42) | GABRA1GABRB2LMNAKMT2AGABRB1 | |
| SCHEMBL6950808 | 0.76 | LMNA (0.42) | GABRA1GABRB2LMNAKMT2AGABRB1 | |
| SCHEMBL24812139 | 0.76 | ALDH1A1 (0.41) | LMNAKMT2APOLBCA1CA2 | |
| SCHEMBL11588112 | 0.76 | CYSLTR2 (0.41) | LMNAKMT2ACYP3A4HTR2CGAA | |
| SCHEMBL10970015 | 0.76 | NPC1 (0.37) | LMNAKMT2APOLBCA1CA2 | |
| SCHEMBL4736600 | 0.75 | ALDH1A1 (0.39) | GABRA1GABRB2KMT2ACA1CA2 | |
| SCHEMBL10824330 | 0.74 | IDO1 (0.47) | KMT2APOLBHPGDTSHRALDH1A1 | |
| SCHEMBL9492144 | 0.74 | POLQ (0.41) | LMNASLC6A2ALDH1A1GAA | |
| SCHEMBL16387187 | 0.73 | CA12 (0.50) | LMNAKMT2APOLBCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061016-A1 | N-SUBSTITUTED PIPERIDINYL 4 -ARYLSULFONAMIDES AS MODULATORS OF THE SECRETED FRIZZLED RELATED PROTEIN- 1 | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |