Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RBP4 | P02753 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.34 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.34 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9492144 | 0.84 | POLQ (0.41) | ALDH1A1KDM4ERAB9ANPSR1GAA | |
| SCHEMBL12379210 | 0.79 | CA2 (0.53) | ALDH1A1TDP1TSHRKDM4ERBP4 | |
| SCHEMBL10970015 | 0.76 | NPC1 (0.37) | ALDH1A1TSHRCA2CA12CA1 | |
| SCHEMBL24812139 | 0.76 | ALDH1A1 (0.41) | ALDH1A1TDP1TSHRKDM4ECA2 | |
| SCHEMBL4735455 | 0.75 | GABRA1 (0.39) | ALDH1A1TSHRCA2P2RX4CETP | |
| SCHEMBL9306266 | 0.75 | RAB9A (0.39) | ALDH1A1TDP1TSHRKDM4ERBP4 | |
| SCHEMBL10824330 | 0.74 | IDO1 (0.47) | ALDH1A1TSHRKDM4EMEN1RAB9A | |
| SCHEMBL8589246 | 0.74 | BCAT2 (0.38) | ALDH1A1CA2CA12CA1CA4 | |
| SCHEMBL9493141 | 0.74 | GAA (0.49) | ALDH1A1TDP1TSHRMEN1RAB9A | |
| SCHEMBL16387187 | 0.73 | CA12 (0.50) | ALDH1A1TSHRKDM4ECA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061016-A1 | N-SUBSTITUTED PIPERIDINYL 4 -ARYLSULFONAMIDES AS MODULATORS OF THE SECRETED FRIZZLED RELATED PROTEIN- 1 | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |