Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 4/20 | 0.39 |
| ▸ | DRD2 | P14416 | 4/20 | 0.39 |
| ▸ | DRD4 | P21917 | 4/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL47362 | 0.88 | GLS (0.40) | SMN1; SMN2HSD17B10KMT2AHTR1ADRD2 | |
| SCHEMBL7877130 | 0.84 | — | — | |
| SCHEMBL9558337 | 0.84 | HTR1A (0.42) | KMT2AHTR1ADRD2DRD4NAMPT | |
| Hydrochloric Acid SCHEMBL22394902 | 0.82 | — | — | |
| SCHEMBL14026314 | 0.80 | — | — | |
| SCHEMBL14419735 | 0.79 | HTT (0.46) | SMN1; SMN2HSD17B10KMT2AHTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL28929577 | 0.78 | SMN1; SMN2 (0.53) | SMN1; SMN2HSD17B10KMT2AEPHX1ALDH1A1 | |
| SCHEMBL47365 | 0.78 | EPHX1 (0.61) | SMN1; SMN2HSD17B10KMT2AEPHX1ALDH1A1 | |
| SCHEMBL22170893 | 0.78 | GNAI3 (0.49) | HTR1ADRD2DRD4NAMPT | |
| SCHEMBL30393917 | 0.78 | HDAC1 (0.40) | SMN1; SMN2HSD17B10KMT2AEPHX1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107987075-B | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | 艾伯维公司 | 2020-12-01 | — | — | CN | disclosed |
| WO-2011157748-A1 | 5-ARYL ISOXAZOLINES FOR CONTROLLING PESTS | NOVARTIS AG (CH) | 2011-12-22 | — | — | WO | disclosed |