Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.35 |
| ▸ | PIP5K1C | O60331 | 3/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | PIP5K1B | O14986 | 1/20 | 0.35 |
| ▸ | PIP5K1A | Q99755 | 1/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL47355 | 0.88 | SMN1; SMN2 (0.41) | HTR1ADRD2DRD4HDAC3HDAC1 | |
| SCHEMBL3663509 | 0.82 | GLS (0.41) | GLSHTR1ADRD2DRD4ACACB | |
| SCHEMBL13702331 | 0.81 | HTR1A (0.41) | GLSHTR1ADRD2DRD4ACACB | |
| SCHEMBL20928257 | 0.78 | CHRNB2 (0.47) | GLSHTR1ADRD2DRD4SMN1; SMN2 | |
| SCHEMBL19550635 | 0.78 | — | — | |
| SCHEMBL2828351 | 0.78 | — | — | |
| SCHEMBL19550602 | 0.78 | — | — | |
| SCHEMBL28361513 | 0.78 | SMN1; SMN2 (0.45) | GLSHTR1ADRD2DRD4ACACB | |
| SCHEMBL7877130 | 0.77 | — | — | |
| SCHEMBL6313794 | 0.77 | HTR1A (0.41) | GLSHTR1ADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582696-B1 | 5-ARYL ISOXAZOLINES FOR CONTROLLING PESTS | NOVARTIS AG (CH) | 2014-10-22 | — | — | EP | disclosed |
| WO-2011157748-A1 | 5-ARYL ISOXAZOLINES FOR CONTROLLING PESTS | NOVARTIS AG (CH) | 2011-12-22 | — | — | WO | disclosed |