Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | AGT | P01019 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4735569 | 0.82 | SOAT1 (0.47) | AGTR1AGTR2MEN1KMT2ALMNA | |
| SCHEMBL9262004 | 0.77 | AGTR1 (0.46) | AGTR1AGTR2TSHRMEN1KMT2A | |
| SCHEMBL9488699 | 0.76 | AGTR1 (0.46) | AGTR1AGTR2MEN1KMT2AAGT | |
| SCHEMBL4672053 | 0.76 | AGTR1 (0.47) | AGTR1AGTR2AGTNPC1RAB9A | |
| SCHEMBL9084585 | 0.75 | AGTR1 (0.47) | AGTR1AGTR2AGT | |
| SCHEMBL4671291 | 0.74 | AGTR1 (0.42) | AGTR1AGTR2AGT | |
| SCHEMBL13146764 | 0.74 | AGTR1 (0.55) | AGTR1AGTR2TSHRLMNAAGT | |
| SCHEMBL841404 | 0.74 | AGTR1 (0.48) | AGTR1AGTR2AGT | |
| SCHEMBL2831925 | 0.74 | AGTR1 (0.46) | AGTR1AGTR2AGTALDH1A1 | |
| SCHEMBL2831924 | 0.74 | AGTR1 (0.46) | AGTR1AGTR2AGTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590343-B1 | SYNTHESIS OF 2-BUTYL-3-(2' -(1-TRITYL-1H-TETRAZOL-5-YL)BIPHEN YL-4-YL)-1,3-DIAZASPIRO-4,4 -NONENE-4-ONE | TEVA PHARMA (IL) | 2008-07-16 | — | — | EP | claimed |