Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.46 |
| ▸ | AGT | P01019 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.30 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.30 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.30 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27531698 | 0.89 | AGTR1 (0.40) | AGTR1AGTR2AGTTSHRALDH1A1 | |
| SCHEMBL30956037 | 0.86 | AGTR1 (0.51) | AGTR1AGTR2AGTTSHRALDH1A1 | |
| SCHEMBL635 | 0.86 | AGTR1 (0.51) | AGTR1AGTR2AGTTSHRALDH1A1 | |
| SCHEMBL8698703 | 0.86 | AGTR1 (0.47) | AGTR1AGTR2AGTTSHRALDH1A1 | |
| SCHEMBL6532773 | 0.82 | AGTR1 (0.46) | AGTR1AGTR2AGTTSHRALDH1A1 | |
| SCHEMBL13146764 | 0.82 | AGTR1 (0.55) | AGTR1AGTR2AGTTSHRKIF11 | |
| SCHEMBL4672053 | 0.81 | AGTR1 (0.47) | AGTR1AGTR2AGTALDH1A1 | |
| SCHEMBL9024777 | 0.80 | AGTR1 (0.51) | AGTR1AGTR2AGTTSHRKIF11 | |
| SCHEMBL30316147 | 0.80 | AGTR1 (0.51) | AGTR1AGTR2AGTTSHRKIF11 | |
| SCHEMBL9025749 | 0.80 | AGTR1 (0.43) | AGTR1AGTR2TSHRALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5407942-A | For treating hypertension, atherosclerosis | BAYER AKTIENGESELLSCHAFT (DE) | 1995-04-18 | — | — | US | disclosed |