Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30582773 | 1.00 | NAAA (0.42) | NAAAHCAR2EPHX1TSHRNPC1 | |
| SCHEMBL30582827 | 1.00 | NAAA (0.42) | NAAAHCAR2EPHX1TSHRNPC1 | |
| SCHEMBL30582775 | 1.00 | NAAA (0.42) | NAAAHCAR2EPHX1TSHRNPC1 | |
| SCHEMBL29419059 | 1.00 | NAAA (0.42) | NAAAHCAR2EPHX1TSHRNPC1 | |
| SCHEMBL30295572 | 1.00 | NAAA (0.42) | NAAAHCAR2EPHX1TSHRNPC1 | |
| SCHEMBL30341731 | 1.00 | NAAA (0.42) | NAAAHCAR2EPHX1TSHRNPC1 | |
| SCHEMBL29619472 | 0.98 | NAAA (0.40) | NAAAHCAR2EPHX1TSHRNPC1 | |
| SCHEMBL30095427 | 0.92 | ACLY (0.44) | — | |
| SCHEMBL29375157 | 0.91 | ALDH1A1 (0.40) | NAAAHCAR2TSHRNPC1RAB9A | |
| SCHEMBL31320880 | 0.84 | NAAA (0.39) | NAAAHCAR2EPHX1TSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008066707-A2 | TARGETING PROHORMONE CONVERTASE ENZYMES TO SUPPRESS POMC-MSH PROCESSING TO INDUCE SKIN LIGHTENING | DANA-FARBER CANCER INSTITUTE (US) | 2008-06-05 | — | — | WO | disclosed |