Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SFRP1 | Q8N474 | 11/20 | 0.57 |
| ▸ | CCR8 | P51685 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 2/20 | 0.51 |
| ▸ | WNT3 | P56703 | 6/20 | 0.51 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4734372 | 0.91 | SFRP1 (0.57) | SFRP1CCR8BRD4WNT3NR1H2 | |
| SCHEMBL4734276 | 0.91 | SFRP1 (0.57) | SFRP1CCR8BRD4WNT3NR1H2 | |
| SCHEMBL4846943 | 0.90 | SFRP1 (0.56) | SFRP1CCR8BRD4WNT3NR1H2 | |
| SCHEMBL4735770 | 0.90 | SFRP1 (0.55) | SFRP1CCR8BRD4WNT3NR1H2 | |
| SCHEMBL4734706 | 0.90 | SFRP1 (0.55) | SFRP1CCR8BRD4WNT3NR1H2 | |
| SCHEMBL4799560 | 0.89 | SFRP1 (0.62) | SFRP1CCR8BRD4WNT3NR1H2 | |
| SCHEMBL4733043 | 0.89 | SFRP1 (0.55) | SFRP1CCR8BRD4WNT3NR1H2 | |
| SCHEMBL4734592 | 0.89 | SFRP1 (0.55) | SFRP1CCR8BRD4WNT3NR1H2 | |
| SCHEMBL4734672 | 0.88 | SFRP1 (0.56) | SFRP1CCR8BRD4WNT3NR1H2 | |
| SCHEMBL4784120 | 0.88 | GPR119 (0.56) | SFRP1CCR8BRD4WNT3NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061016-A1 | N-SUBSTITUTED PIPERIDINYL 4 -ARYLSULFONAMIDES AS MODULATORS OF THE SECRETED FRIZZLED RELATED PROTEIN- 1 | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |