Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4739791 | 0.89 | TSHR (0.36) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL4737293 | 0.88 | ALDH1A1 (0.37) | ALDH1A1KDM4EHPGDTDP1L3MBTL1 | |
| SCHEMBL4737295 | 0.88 | ALDH1A1 (0.37) | ALDH1A1KDM4EHPGDTDP1L3MBTL1 | |
| SCHEMBL4737617 | 0.78 | TSHR (0.33) | ALDH1A1KMT2AMEN1TSHRSMN1; SMN2 | |
| SCHEMBL4738147 | 0.76 | NQO2 (0.42) | ALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL4736257 | 0.76 | ALDH1A1 (0.32) | ALDH1A1KDM4EL3MBTL1KMT2AMAPT | |
| SCHEMBL4664575 | 0.74 | KMT2A (0.41) | ALDH1A1KDM4EHPGDKMT2AMAPT | |
| SCHEMBL4737211 | 0.74 | CYP19A1 (0.34) | KMT2APOLBMAPTMEN1RAB9A | |
| SCHEMBL5116642 | 0.73 | GAA (0.43) | ALDH1A1KDM4EHPGDL3MBTL1KMT2A | |
| SCHEMBL4735946 | 0.73 | ELANE (0.40) | ALDH1A1KDM4EHPGDL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008071765-A1 | PHARMACEUTICALLY ACTIVE SPIRO-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | NYCOMED GMBH (DE) | 2008-06-19 | — | — | WO | disclosed |