SCHEMBL9951880

SCHEMBL9951880

CCCCCCCCCCCCCC(=O)C(OP(=O)(O)OCCN)[C@H](CO)OO

nearest known ligand 0.45

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PLA2G2C Q5R387 2/20 0.45
P2RY10 O00398 8/20 0.38
GPR34 Q9UPC5 3/20 0.38
PLA2G2D Q9UNK4 1/20 0.36
GPR174 Q9BXC1 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9951445 1.00 PLA2G2C (0.45) PLA2G2CP2RY10GPR34PLA2G2DGPR174
SCHEMBL4737508 1.00 PLA2G2C (0.45) PLA2G2CP2RY10GPR34PLA2G2DGPR174
SCHEMBL8628861 0.94 P2RY10 (0.43) P2RY10GPR34
SCHEMBL8627715 0.91 S1PR1 (0.46) P2RY10GPR34
SCHEMBL9166758 0.86 PLA2G2C (0.43) PLA2G2CP2RY10GPR34
SCHEMBL6372215 0.86 PLA2G2C (0.46) PLA2G2CP2RY10GPR34PLA2G2DGPR174
SCHEMBL15022342 0.86 PLA2G2C (0.46) PLA2G2CP2RY10GPR34PLA2G2DGPR174
SCHEMBL16964730 0.84 P2RY10 (0.43) PLA2G2CP2RY10GPR34
SCHEMBL17595343 0.83 S1PR1 (0.49) P2RY10GPR34
SCHEMBL9951988 0.83 S1PR1 (0.49) P2RY10GPR34

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3458474-A1 COMBINATIONS OF MRNAS ENCODING IMMUNE MODULATING POLYPEPTIDES AND USES THEREOF Modernatx, Inc. (US) 2019-03-27 EP disclosed
WO-2017201325-A1 COMBINATIONS OF MRNAS ENCODING IMMUNE MODULATING POLYPEPTIDES AND USES THEREOF MODERNATX, INC. (US) 2017-11-23 WO disclosed
EP-2654779-A1 LIPOSOMAL FORMULATION OF NONGLYCOSIDIC CERAMIDES AND USES THEREOF Ludwig Institute for Cancer Research, Ltd. (US) 2013-10-30 EP disclosed
WO-2012088414-A1 LIPOSOMAL FORMULATION OF NONGLYCOSIDIC CERAMIDES AND USES THEREOF LUDWIG INSTITUTE FOR CANCER RESEARCH LTD. (US) 2012-06-28 WO disclosed