Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | KRAS | P01116 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737599 | 1.00 | DPP4 (0.48) | DPP4ALOX5CYP1B1ABCG2MAOA | |
| SCHEMBL4739052 | 0.87 | TNFRSF1A (0.54) | DPP4CYP1B1ABCG2MAOALMNA | |
| SCHEMBL4740485 | 0.87 | TNFRSF1A (0.54) | DPP4CYP1B1ABCG2MAOALMNA | |
| SCHEMBL4737507 | 0.86 | PPARG (0.57) | ABCG2LMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL4787159 | 0.86 | TNFRSF1A (0.55) | DPP4CYP1B1MAOBTNFRSF1ACXCL12 | |
| SCHEMBL4737511 | 0.86 | PPARG (0.57) | ABCG2LMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL4737608 | 0.86 | TNFRSF1A (0.55) | DPP4CYP1B1MAOBTNFRSF1ACXCL12 | |
| SCHEMBL4741100 | 0.85 | PPARG (0.46) | ABCG2LMNAMAPTATMSMN1; SMN2 | |
| SCHEMBL4738535 | 0.85 | PPARG (0.44) | CYP1B1ABCG2LMNAMAPTATM | |
| SCHEMBL4738538 | 0.85 | PPARG (0.44) | CYP1B1ABCG2LMNAMAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | claimed |
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |