Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | TNFRSF1A | P19438 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4740248 | 1.00 | PPARG (0.46) | PPARGPPARAMAOBSMN1; SMN2NPC1 | |
| SCHEMBL4739052 | 0.89 | TNFRSF1A (0.54) | MAOBSMN1; SMN2NPC1ALDH1A1RAB9A | |
| SCHEMBL4740485 | 0.89 | TNFRSF1A (0.54) | MAOBSMN1; SMN2NPC1ALDH1A1RAB9A | |
| SCHEMBL4738538 | 0.87 | PPARG (0.44) | PPARGPPARAMAOBSMN1; SMN2NPC1 | |
| SCHEMBL4738535 | 0.87 | PPARG (0.44) | PPARGPPARAMAOBSMN1; SMN2NPC1 | |
| SCHEMBL4737599 | 0.85 | DPP4 (0.48) | PPARGPPARAMAOBSMN1; SMN2NPC1 | |
| SCHEMBL4737596 | 0.85 | DPP4 (0.48) | PPARGPPARAMAOBSMN1; SMN2NPC1 | |
| SCHEMBL4737608 | 0.83 | TNFRSF1A (0.55) | MAOBTNFRSF1A | |
| SCHEMBL4787159 | 0.83 | TNFRSF1A (0.55) | MAOBTNFRSF1A | |
| SCHEMBL4737511 | 0.83 | PPARG (0.57) | PPARGPPARAMAOBSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | claimed |
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |