Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.44 |
| ▸ | PPARA | Q07869 | 4/20 | 0.44 |
| ▸ | TNFRSF1A | P19438 | 3/20 | 0.44 |
| ▸ | FABP2 | P12104 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4738538 | 1.00 | PPARG (0.44) | PPARGPPARATNFRSF1AFABP2SLC22A12 | |
| SCHEMBL4739052 | 0.89 | TNFRSF1A (0.54) | TNFRSF1ACYP1A1CYP1B1MAPTLMNA | |
| SCHEMBL4740485 | 0.89 | TNFRSF1A (0.54) | TNFRSF1ACYP1A1CYP1B1MAPTLMNA | |
| SCHEMBL4737608 | 0.88 | TNFRSF1A (0.55) | TNFRSF1ACYP1A1CYP1B1MAOB | |
| SCHEMBL4787159 | 0.88 | TNFRSF1A (0.55) | TNFRSF1ACYP1A1CYP1B1MAOB | |
| SCHEMBL4741100 | 0.87 | PPARG (0.46) | PPARGPPARATNFRSF1AMAPTLMNA | |
| SCHEMBL4740248 | 0.87 | PPARG (0.46) | PPARGPPARATNFRSF1AMAPTLMNA | |
| SCHEMBL4740257 | 0.86 | PPARG (0.44) | PPARGPPARATNFRSF1ACYP1A1CYP1B1 | |
| SCHEMBL4787472 | 0.86 | PPARG (0.44) | PPARGPPARATNFRSF1ACYP1A1CYP1B1 | |
| SCHEMBL4737599 | 0.85 | DPP4 (0.48) | PPARGPPARATNFRSF1ACYP1B1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | claimed |
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |