Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.52 |
| ▸ | DPP4 | P27487 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4739052 | 1.00 | TNFRSF1A (0.54) | TNFRSF1AMAOBMAPTLMNASMN1; SMN2 | |
| SCHEMBL4741100 | 0.89 | PPARG (0.46) | TNFRSF1AMAOBMAPTLMNASMN1; SMN2 | |
| SCHEMBL4738535 | 0.89 | PPARG (0.44) | TNFRSF1AMAOBMAPTLMNASMN1; SMN2 | |
| SCHEMBL4740248 | 0.89 | PPARG (0.46) | TNFRSF1AMAOBMAPTLMNASMN1; SMN2 | |
| SCHEMBL4738538 | 0.89 | PPARG (0.44) | TNFRSF1AMAOBMAPTLMNASMN1; SMN2 | |
| SCHEMBL4737599 | 0.87 | DPP4 (0.48) | TNFRSF1AMAOBMAPTLMNASMN1; SMN2 | |
| SCHEMBL4737596 | 0.87 | DPP4 (0.48) | TNFRSF1AMAOBMAPTLMNASMN1; SMN2 | |
| SCHEMBL4737511 | 0.85 | PPARG (0.57) | TNFRSF1AMAOBMAPTLMNASMN1; SMN2 | |
| SCHEMBL4737608 | 0.85 | TNFRSF1A (0.55) | TNFRSF1AMAOBDPP4CYP1B1CYP1A1 | |
| SCHEMBL4787159 | 0.85 | TNFRSF1A (0.55) | TNFRSF1AMAOBDPP4CYP1B1CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | claimed |
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |