Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 11/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 11/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4736804 | 1.00 | TNFRSF1A (0.46) | TNFRSF1ACYP1A1CYP1B1DPP4MAOB | |
| SCHEMBL4787159 | 0.87 | TNFRSF1A (0.55) | TNFRSF1ACYP1A1CYP1B1DPP4MAOB | |
| SCHEMBL4737608 | 0.87 | TNFRSF1A (0.55) | TNFRSF1ACYP1A1CYP1B1DPP4MAOB | |
| SCHEMBL4739835 | 0.80 | CYP1A1 (0.49) | CYP1A1CYP1B1DPP4MAOB | |
| SCHEMBL4739838 | 0.80 | CYP1A1 (0.49) | CYP1A1CYP1B1DPP4MAOB | |
| SCHEMBL4738538 | 0.80 | PPARG (0.44) | TNFRSF1ACYP1A1CYP1B1MAOB | |
| SCHEMBL4738535 | 0.80 | PPARG (0.44) | TNFRSF1ACYP1A1CYP1B1MAOB | |
| SCHEMBL4737599 | 0.78 | DPP4 (0.48) | TNFRSF1ACYP1B1DPP4MAOB | |
| SCHEMBL4737596 | 0.78 | DPP4 (0.48) | TNFRSF1ACYP1B1DPP4MAOB | |
| SCHEMBL4740485 | 0.78 | TNFRSF1A (0.54) | TNFRSF1ACYP1A1CYP1B1DPP4MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |