Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | GUSB | P08236 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4736438 | 0.81 | KMT2A (0.58) | KMT2AHPGDMEN1TP53ALOX12 | |
| SCHEMBL4784271 | 0.81 | KMT2A (0.57) | KMT2AHPGDMEN1TP53ALOX12 | |
| SCHEMBL14147625 | 0.76 | KMT2A (0.54) | KMT2AHPGDMEN1TP53ALOX12 | |
| SCHEMBL4738132 | 0.75 | HPGD (0.52) | KMT2AHPGDMEN1TP53ALOX12 | |
| SCHEMBL4783417 | 0.74 | HPGD (0.51) | KMT2AHPGDMEN1TP53ALOX12 | |
| SCHEMBL4738824 | 0.73 | RAB9A (0.55) | KMT2AHPGDMEN1TP53ALOX12 | |
| SCHEMBL14146845 | 0.73 | HRH4 (0.53) | KMT2AHPGDMEN1TP53ALOX12 | |
| SCHEMBL14146842 | 0.72 | AKR1C3 (0.52) | KMT2AHPGDMEN1TP53ALOX12 | |
| SCHEMBL16163670 | 0.70 | LMNA (0.49) | KMT2AHPGDMEN1TP53ALDH1A1 | |
| SCHEMBL4784009 | 0.69 | ALDH1A1 (0.48) | KMT2AHPGDMEN1TP53ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008085008-A1 | T-CELL INHIBITING COMPOUNDS AND THEIR USE FOR THE TREATMENT OF T-CELL-MEDIATED DISEASES | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2008-07-17 | — | — | WO | claimed |
| WO-2008085008-A1 | T-CELL INHIBITING COMPOUNDS AND THEIR USE FOR THE TREATMENT OF T-CELL-MEDIATED DISEASES | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2008-07-17 | — | — | WO | disclosed |
| WO-2008085008-A1 | T-CELL INHIBITING COMPOUNDS AND THEIR USE FOR THE TREATMENT OF T-CELL-MEDIATED DISEASES | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2008-07-17 | — | — | WO | disclosed |