Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 1/20 | 0.46 |
| ▸ | SCD | O00767 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.43 |
| ▸ | KDM5A | P29375 | 1/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4738880 | 0.81 | RBP4 (0.47) | RBP4SCDKDM4CKDM5AKDM5B | |
| Trifluoroacetic Acid SCHEMBL4737904 | 0.81 | KDM4C (0.50) | RBP4SCDKDM4CKDM5AKDM5B | |
| SCHEMBL18367381 | 0.80 | CDK5 (0.53) | RBP4SCDKDM4CKDM5AKDM5B | |
| SCHEMBL4735220 | 0.79 | RBP4 (0.51) | RBP4SCDKDM4CKDM5AKDM5B | |
| SCHEMBL4735031 | 0.77 | SCD (0.32) | SCD | |
| SCHEMBL9248509 | 0.77 | LMNA (0.60) | RBP4KDM4CKDM5AKDM5BKLKB1 | |
| SCHEMBL3688462 | 0.77 | KDM4C (0.57) | RBP4KDM4CKDM5AKDM5BKLKB1 | |
| SCHEMBL4737896 | 0.76 | BRD4 (0.41) | KLKB1RIPK1 | |
| SCHEMBL23830229 | 0.76 | KLKB1 (0.52) | RBP4SCDKLKB1TSHRCYP3A4 | |
| SCHEMBL24310642 | 0.75 | KDM4C (0.52) | RBP4KDM4CKDM5AKDM5BKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |