Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733881 | 0.80 | GABRG2 (0.35) | — | |
| Trifluoroacetic Acid SCHEMBL4735033 | 0.78 | PLA2G4A (0.36) | ARCNR2 | |
| SCHEMBL4737902 | 0.77 | RBP4 (0.46) | SCD | |
| SCHEMBL4738757 | 0.76 | PLA2G4A (0.40) | CNR2 | |
| SCHEMBL31332879 | 0.74 | MEN1 (0.42) | SCDCNR2 | |
| SCHEMBL16563562 | 0.69 | CNR2 (0.39) | SCDCNR2 | |
| SCHEMBL21063624 | 0.68 | KDM2B (0.33) | — | |
| SCHEMBL21314975 | 0.66 | MEN1 (0.40) | SCD | |
| Trifluoroacetic Acid SCHEMBL4738880 | 0.64 | RBP4 (0.47) | SCD | |
| SCHEMBL7425205 | 0.63 | SMYD3 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |