Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4740303 | 0.85 | ALDH1A1 (0.35) | MEN1KMT2APOLBMAOBALDH1A1 | |
| SCHEMBL17844294 | 0.84 | TAS2R38 (0.43) | MEN1KMT2AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL4738754 | 0.77 | KMT2A (0.39) | MEN1KMT2APOLBALDH1A1GAA | |
| SCHEMBL5227550 | 0.73 | — | — | |
| SCHEMBL9247348 | 0.72 | — | — | |
| SCHEMBL4736058 | 0.71 | KDM4E (0.43) | MEN1KMT2APOLBALDH1A1GAA | |
| SCHEMBL4741227 | 0.70 | MAPT (0.47) | MEN1KMT2AALDH1A1GAALMNA | |
| SCHEMBL6555243 | 0.68 | TAS2R38 (0.38) | MEN1KMT2APOLBMAOBMAOA | |
| SCHEMBL4739774 | 0.65 | — | — | |
| SCHEMBL3080784 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008077170-A2 | BENZOTHIOAMIDES, AND USE THEREOF FOR RELAXING SMOOTH MUSCLES | Universität Wien (AT) | 2008-07-03 | — | — | WO | disclosed |