Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R38 | P59533 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844294 | 0.83 | TAS2R38 (0.43) | TAS2R38HSD17B10ALDH1A1CYP3A4KMT2A | |
| SCHEMBL8309546 | 0.76 | FYN (0.47) | NPC1RAB9A | |
| SCHEMBL8305510 | 0.76 | CA12 (0.34) | — | |
| SCHEMBL8308422 | 0.73 | ACHE (0.36) | — | |
| SCHEMBL7516507 | 0.72 | PNMT (0.42) | — | |
| SCHEMBL8307723 | 0.72 | DRD2 (0.32) | RAB9A | |
| SCHEMBL8309882 | 0.72 | DRD2 (0.46) | — | |
| SCHEMBL5077456 | 0.72 | ALDH1A1 (0.53) | TAS2R38HSD17B10ALDH1A1CYP3A4KMT2A | |
| SCHEMBL7513395 | 0.71 | MAOA (0.39) | HSD17B10ALDH1A1MAOATSHR | |
| SCHEMBL7510864 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1233786-B1 | PRODUCT COMPRISING AT LEAST A NO SYNTHASE INHIBITING SUBSTANCE ASSOCIATED WITH AT LEAST A PHOSPHOLIPASE A2 INHIBITING SUBSTANCE FOR THE PREPARATION OF A MEDICAMENT | CONSEILS DE RECH SET D APPLIC (FR) | 2004-02-18 | — | — | EP | claimed |