SCHEMBL473811

SCHEMBL473811

CCCCC(CC)COc1ccc(-c2ncnc(-c3ccc(OC)cc3)n2)c(O)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.41
HTT P42858 4/20 0.41
TDP1 Q9NUW8 1/20 0.41
MAPT P10636 9/20 0.40
KMT2A Q03164 2/20 0.38
NPC1 O15118 2/20 0.38
MEN1 O00255 1/20 0.38
CNR1 P21554 1/20 0.38
CNR2 P34972 1/20 0.38
GPR35 Q9HC97 1/20 0.38
GPR55 Q9Y2T6 1/20 0.38
MAPK1 P28482 4/20 0.36
TP53 P04637 2/20 0.36
TSHR P16473 2/20 0.36
MAPK10 P53779 2/20 0.36
PTK2B Q14289 1/20 0.36
NCOA1 Q15788 1/20 0.36
NCOA3 Q9Y6Q9 1/20 0.36
IDH1 O75874 1/20 0.36
ALDH1A1 P00352 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30111341 1.00 LMNA (0.41) LMNAHTTTDP1MAPTKMT2A
SCHEMBL28482241 0.94 LMNA (0.37) LMNAHTTTDP1MAPTKMT2A
Bemotrizinol SCHEMBL29350308 0.93 TDP1 (0.43) LMNAHTTTDP1MAPTKMT2A
SCHEMBL10195000 0.93 TDP1 (0.43) LMNAHTTTDP1MAPTKMT2A
Bemotrizinol SCHEMBL29360093 0.93 TDP1 (0.43) LMNAHTTTDP1MAPTKMT2A
Bemotrizinol SCHEMBL77320 0.93 TDP1 (0.43) LMNAHTTTDP1MAPTKMT2A
SCHEMBL22854980 0.92 TDP1 (0.42) LMNAHTTTDP1MAPTKMT2A
SCHEMBL29365165 0.92 LMNA (0.40) LMNATDP1MAPTKMT2ANPC1
SCHEMBL579788 0.92 LMNA (0.40) LMNATDP1MAPTKMT2ANPC1
SCHEMBL28344806 0.91 LMNA (0.39) LMNAHTTMAPTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116547346-A Additive mixture 巴斯夫欧洲公司 2023-08-04 CN claimed
CN-115947899-A Light-cured resin composition and light-cured product 杭州先临齿科技术有限公司 2023-04-11 CN claimed
WO-2021069158-A1 SUNSCREEN CONTAINING A NATURAL, FILM-FORMING POLYMER BEIERSDORF AG (DE) 2021-04-15 WO claimed
US-20210085581-A1 SUNSCREEN AGENT WITH A PROTECTION AGAINST TEXTILE SPOTTING DUE TO 4-(TERT.-BUTYL)-4'-METHOXYDIBENZOYLMETHANE BEIERSDORF AG (DE) 2021-03-25 US claimed
EP-3687630-A1 COSMETIC PREPARATION CONTAINING CETYL-DIGLYCERYL TRIS(TRIMETHYLSILOXY)SILYLETHYL DIMETHICONE Beiersdorf AG (DE) 2020-08-05 EP claimed
US-20200163852-A1 SUNSCREEN AGENT WITH PROTECTION AGAINST TEXTILE SPOTTING DUE TO HEXYL 2-[4-(DIETHYLAMINO)-2-HYDROXYBENZOYL]BENZOATE BEIERSDORF AG (DE) 2020-05-28 US claimed
EP-3554462-A1 METHOD FOR IMPROVING THE SENSORIAL PROPERTIES OF OIL-IN-WATER EMULSIONS Société d'Exploitation de Produits pour les Industries Chimiques SEPPIC (FR) 2019-10-23 EP claimed
EP-1618868-B1 Process for photostabilising a dibenzoylmethane derivative with an arylalkyl benzoate derivative and a bis-resorcinyl triazine compound and sunscreening cosmetic compositions ORÉAL L (FR) 2015-11-04 EP claimed
CN-104800092-A Ockereline-free sunscreen with minimal tack BEIERSDORF AG 2015-07-29 CN claimed
US-20140170085-A1 COSMETIC PREPARATION TAILORED TO THE INDIVIDUAL USER AND PROCESS FOR PRODUCING SAME BEIERSDORF AG (DE) 2014-06-19 US claimed
US-20050238610-A1 Low-viscosity emulsions BEIERSDORF AG 2005-10-27 US claimed
US-20050008587-A1 Cosmetic and dermatological photoprotective formulations with a content of hydroxybenzophenones, triazine derivatives and/or benzotriazole derivatives BEIERSDORF AG (DE) 2005-01-13 US claimed
EP-1150649-B1 COSMETIC COMPOSITIONS FOR PHOTOPROTECTION OF THE SKIN AND/OR HAIR CONTAINING A BENZOTRIAZOLE SILICONE DERIVATIVE AND A TRIAZINE BIS-RESORCINYL DERIVATIVE OREAL (FR) 2004-11-24 EP claimed
EP-1040820-B1 Cosmetic sunscreen compositions based on synergic filter mixtures and their uses OREAL (FR) 2004-06-23 EP claimed
EP-1355622-A1 FILTERING COMPOSITIONS COMPRISING A 1,3,5-TRIAZINE DERIVATIVE AND A TRICARBOXYLIC ACID TRIESTER AND USES THEREOF L'OREAL (FR) 2003-10-29 EP claimed
WO-2002056851-A1 FILTERING COMPOSITIONS COMPRISING A 1,3,5-TRIAZINE DERIVATIVE AND A TRICARBOXYLIC ACID TRIESTER AND USES THEREOF L'OREAL (FR) 2002-07-25 WO claimed
EP-1043014-A1 Cosmetic sunscreen compositions based on a synergic filter mixture and their uses L'OREAL (FR) 2000-10-11 EP claimed
EP-1043013-A1 Photoprotective compositions containing a benzotriazole derivative, a bis-resorcinyl triazine derivative and a compound having benzoazolyl- or benzodiazolyl groups L'OREAL (FR) 2000-10-11 EP claimed
EP-1040820-A1 Cosmetic sunscreen compositions based on synergic filter mixtures and their uses L'OREAL (FR) 2000-10-04 EP claimed
EP-1027881-A1 Photoprotective compositions containing a bisresorcinyl triazine derivative and a compound with benzoazolyl or benzodiazolyl groups L'OREAL (FR) 2000-08-16 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050008587-A1 Cosmetic and dermatological photoprotective formulations with a content of hydroxybenzophenones, triazine derivatives and/or benzotriazole derivatives TYR, MITF, CUTA LMNA 2704/4885HTT 41/4885TDP1 859/4885
US-20050238610-A1 Low-viscosity emulsions SGMS2, SGMS1, DEGS1 LMNA 839/4885HTT 2033/4885TDP1 1510/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.