Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | ACACA | Q13085 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | NCF1 | P14598 | 1/20 | 0.32 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15415201 | 0.83 | PLD1 (0.38) | KDM4EMEN1KMT2AADRB2NCF1 | |
| SCHEMBL2649063 | 0.79 | ADRA1A (0.37) | ADRA1AADRA1BKDM4EMEN1KMT2A | |
| SCHEMBL8915788 | 0.75 | HTR2C (0.40) | — | |
| SCHEMBL4826186 | 0.74 | PRKCQ (0.41) | ADRA1AADRA1BHRH4ADRB2NCF1 | |
| SCHEMBL8219392 | 0.73 | ADRB1 (0.49) | ADRA1AADRA1B | |
| SCHEMBL30777649 | 0.73 | ADRB1 (0.49) | ADRA1AADRA1B | |
| SCHEMBL15415762 | 0.72 | ALDH1A1 (0.35) | ADRA1AADRA1BKDM4EMEN1KMT2A | |
| SCHEMBL8917894 | 0.72 | HTR2C (0.38) | ADRA1AADRA1BHRH4 | |
| SCHEMBL3545485 | 0.72 | KDM4E (0.44) | KDM4EMEN1KMT2A | |
| SCHEMBL3764755 | 0.71 | CKS1B (0.39) | ADRA1AADRA1BKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | claimed |
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | disclosed |