Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | PPARA | Q07869 | 3/20 | 0.44 |
| ▸ | TNFRSF1A | P19438 | 3/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4740257 | 1.00 | PPARG (0.44) | PPARGPPARATNFRSF1ACYP1A1CYP1B1 | |
| SCHEMBL4737415 | 0.86 | ALOX5 (0.46) | PPARGPPARATNFRSF1ACYP1A1CYP1B1 | |
| SCHEMBL4737414 | 0.86 | ALOX5 (0.46) | PPARGPPARATNFRSF1ACYP1A1CYP1B1 | |
| SCHEMBL4738538 | 0.86 | PPARG (0.44) | PPARGPPARATNFRSF1ACYP1A1CYP1B1 | |
| SCHEMBL4738535 | 0.86 | PPARG (0.44) | PPARGPPARATNFRSF1ACYP1A1CYP1B1 | |
| SCHEMBL4741758 | 0.80 | GABRA3 (0.48) | TNFRSF1ACYP1A1CYP1B1ABCG2MAOB | |
| SCHEMBL4741756 | 0.80 | GABRA3 (0.48) | TNFRSF1ACYP1A1CYP1B1ABCG2MAOB | |
| SCHEMBL12464057 | 0.74 | PPARA (0.71) | PPARGPPARAPPARD | |
| SCHEMBL4740485 | 0.74 | TNFRSF1A (0.54) | TNFRSF1ACYP1A1CYP1B1ABCG2MAOB | |
| SCHEMBL4739052 | 0.74 | TNFRSF1A (0.54) | TNFRSF1ACYP1A1CYP1B1ABCG2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | claimed |
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |