SCHEMBL4738898

SCHEMBL4738898

OCC1Cc2ccccc2[C]N1

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TRPM5 Q9NZQ8 6/20 0.37
TRPM4 Q8TD43 2/20 0.36
PRKCD Q05655 5/20 0.36
PRKCG P05129 1/20 0.36
PRKCA P17252 1/20 0.36
PNMT P11086 2/20 0.36
CREBBP Q92793 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3370161 0.76 CYP2D6 (0.32)
SCHEMBL1828173 0.72 TSHR (0.42) CREBBP
SCHEMBL3374279 0.70 MAPT (0.53)
SCHEMBL4161186 0.69 MAPT (0.37) PNMT
SCHEMBL550431 0.68 CREBBP (0.59) TRPM5PRKCDPRKCGPRKCAPNMT
SCHEMBL894207 0.68 PNMT (0.67) PNMT
SCHEMBL4738129 0.68 PNMT (0.67) PNMT
SCHEMBL894205 0.68 PNMT (0.67) PNMT
SCHEMBL1193549 0.68 CREBBP (0.59) TRPM5PRKCDPRKCGPRKCAPNMT
SCHEMBL2450511 0.68 CREBBP (0.59) TRPM5PRKCDPRKCGPRKCAPNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008072850-A1 TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE AMOREPACIFIC CORPORATION (KR) 2008-06-19 WO claimed
WO-2008072850-A1 TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE AMOREPACIFIC CORPORATION (KR) 2008-06-19 WO disclosed