Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1828173 | 0.76 | TSHR (0.42) | — | |
| SCHEMBL4738898 | 0.76 | TRPM5 (0.37) | — | |
| SCHEMBL3374279 | 0.74 | MAPT (0.53) | CYP2D6MEN1KMT2AGAAMAPT | |
| SCHEMBL3921328 | 0.71 | MAPT (0.41) | MEN1KMT2AGAAMAPT | |
| SCHEMBL4161186 | 0.70 | MAPT (0.37) | MEN1KMT2AGAAMAPT | |
| SCHEMBL1444986 | 0.69 | IDO1 (0.41) | ANPEP | |
| SCHEMBL6962983 | 0.68 | ANPEP (0.33) | CYP2D6MEN1RECQLKMT2AANPEP | |
| SCHEMBL4407901 | 0.68 | ANPEP (0.33) | CYP2D6MEN1RECQLKMT2AANPEP | |
| SCHEMBL6141217 | 0.66 | PNMT (0.35) | CYP2D6MAPT | |
| SCHEMBL9510934 | 0.65 | ANPEP (0.39) | ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100324091-A1 | Pyrazolone Derivative | KOWA COMPANY, LTD. (JP) | 2010-12-23 | — | — | US | disclosed |
| EP-2172458-A1 | PYRAZOLONE DERIVATIVE | Kowa Company, Ltd. (JP) | 2010-04-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324091-A1 | Pyrazolone Derivative | SERPINE1, SERPINC1, TFPI | CYP2D6 1265/4885MEN1 2985/4885RECQL 2623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.