Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.55 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.48 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 1/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.48 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.48 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.48 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.48 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26324037 | 0.80 | APLNR (0.65) | APLNRPOLBALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL2226834 | 0.79 | APLNR (0.63) | APLNRPOLBALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL5332226 | 0.78 | QPCT (0.51) | APLNRPTPN7DUSP3ALDH1A1TSHR | |
| SCHEMBL20496920 | 0.77 | APLNR (0.61) | APLNRALDH1A1TAS1R3TAS1R1TSHR | |
| SCHEMBL4738279 | 0.76 | DUSP3 (0.71) | PTPN7DUSP3POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL18415441 | 0.75 | TAS1R3 (0.67) | APLNRPOLBALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL3964252 | 0.74 | APLNR (0.50) | APLNRPOLBALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL10915036 | 0.74 | CNR1 (0.61) | APLNRPOLBALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL5331053 | 0.74 | QPCT (0.46) | APLNRPTPN7DUSP3ALDH1A1TSHR | |
| SCHEMBL933063 | 0.74 | APLNR (0.76) | APLNRALDH1A1TAS1R3TAS1R1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008077170-A2 | BENZOTHIOAMIDES, AND USE THEREOF FOR RELAXING SMOOTH MUSCLES | Universität Wien (AT) | 2008-07-03 | — | — | WO | disclosed |