Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 1/20 | 0.51 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.48 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.48 |
| ▸ | APLNR | P35414 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | STAT1 | P42224 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5331053 | 0.87 | QPCT (0.46) | QPCTPTPN7DUSP3APLNRTSHR | |
| SCHEMBL5329065 | 0.86 | LMNA (0.60) | TSHRALDH1A1NPSR1MAPTTP53 | |
| SCHEMBL4739043 | 0.78 | APLNR (0.55) | QPCTPTPN7DUSP3APLNRTSHR | |
| SCHEMBL5327555 | 0.78 | SMN1; SMN2 (0.46) | QPCTPTPN7DUSP3APLNRTSHR | |
| SCHEMBL26324037 | 0.74 | APLNR (0.65) | QPCTAPLNRTSHRALDH1A1NPSR1 | |
| SCHEMBL5328751 | 0.73 | TP53 (0.56) | TSHRALDH1A1NPSR1MAPTTP53 | |
| SCHEMBL2226834 | 0.73 | APLNR (0.63) | QPCTAPLNRTSHRALDH1A1NPSR1 | |
| SCHEMBL20496920 | 0.72 | APLNR (0.61) | QPCTAPLNRTSHRALDH1A1NPSR1 | |
| SCHEMBL7014019 | 0.71 | TSHR (0.59) | TSHRALDH1A1NPSR1MAPTTP53 | |
| SCHEMBL13491562 | 0.70 | HTT (0.46) | PTPN7DUSP3ALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007138112-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | claimed |
| WO-2007138112-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | disclosed |