Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 4/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 6/20 | 0.45 |
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | APLNR | P35414 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5328751 | 0.87 | TP53 (0.56) | TP53RXFP1LMNATSHRKMT2A | |
| SCHEMBL5332226 | 0.87 | QPCT (0.51) | QPCTTP53LMNATSHRCYP1A2 | |
| SCHEMBL4739043 | 0.74 | APLNR (0.55) | QPCTTSHRMEN1KMT2AAPLNR | |
| SCHEMBL5327555 | 0.74 | SMN1; SMN2 (0.46) | QPCTTP53LMNATSHRCYP1A2 | |
| SCHEMBL13491562 | 0.74 | HTT (0.46) | LMNAALOX15MEN1KMT2AALDH1A1 | |
| SCHEMBL5329065 | 0.73 | LMNA (0.60) | TP53LMNATSHRALDH1A1NPSR1 | |
| SCHEMBL29096117 | 0.73 | PDGFRB (0.62) | LMNACYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL7014023 | 0.72 | ALDH1A1 (0.59) | TP53RXFP1TSHRHSD17B10MEN1 | |
| SCHEMBL7014019 | 0.72 | TSHR (0.59) | TP53RXFP1LMNATSHRHSD17B10 | |
| SCHEMBL7014974 | 0.72 | MAPT (0.49) | TP53RXFP1LMNATSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007138112-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | claimed |
| WO-2007138112-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | disclosed |